Cutting Edge Personalized Medicine for Asthma & Allergies

Swelling (Angioedema) and HAE

Sweling (Angioedema)

Swelling, also known as angioedema, is a common symptom of an allergic reaction. Swelling occurs when fluid collects in your skin. Allergic swelling often affects your lips, eyes, and face, although it can develop anywhere in your body. Swelling of the face, mouth and throat are often a sign of anaphylaxis and should be treated as a medical emergency. 

Angioedema can be genetic, but it is more often due to an allergic reaction to substances such as:

  • Latex
  • Pet dander
  • Pollen
  • Foods
  • Insect bites
  • Medications such as penicillin or aspirin
  • Sunlight
  • Hot or cold temperatures

The team of specialists at Columbia Allergy provide extensive allergy testing to help you determine the cause of your swelling. This may include skin prick tests, patch tests, intradermal tests, and food challenges. Your provider will create an individualized treatment plan to manage an episode of swelling and prevent further episodes from occurring. Our Columbia Allergy team may recommend carrying an epinephrine auto-injector, undergoing oral immunotherapy (OIT), sublingual immunotherapy (SLIT), subcutaneous immunotherapy (allergy shots). You may even be a candidate for ultrasound-guided intralymphatic immunotherapy (ILIT) at our office in Fremont, CA! 


Hereditary angioedema, also referred to as HAE, is a condition in which a person develops self-limited swelling of skin and mucosal layers as a result of a genetic defect. The swelling can occur anywhere on the body including: hands, feet, face and throat. The swelling can potentially be life threatening if a patient’s airway swells shut. A person may develop episodes of swelling after stress, an illness, physical trauma, or an unknown cause. 

Our providers at Columbia Allergy will perform a thorough workup to confirm whether this is the cause of your swelling. The workup may involve allergy testing to rule out an allergic reaction as the cause of the swelling in addition to labs to test for this genetic condition. Once the diagnosis is confirmed, providers can prescribe injectable medication to help reduce attacks. 

If you are suffering from angioedema or HAE, call your nearest location or schedule an appointment online today!

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Monica H.
“First time at allergy specialist they really care about my kids lifestyle they care more about their patients that their wallet. Now days that's a keeper.. ”

David W.
“Adam and the staff were great at considering my concerns, explaining my results and listening to my questions. Plus everyone was on time and things moved swiftly. ”

Prashant S.
“Absolutely exceptional. The doctor, team and facilities are the best you could ask for. We have never felt more comfortable and safe. With the approach we have taken with our son and has made the whole process so much easier. You guys makes difference in people’s lives”
Noah J.
“Nothing worse than worrying about every cookie and ice cream snack out there that sends us to the ER. Dr.Jain and Dr. Gandhe who are the best. Their expertise and kindness have given us back both dessert and peace of mind. I don't know which one is more appreciated. ”
Hana L.
"Dr.Gandhe always puts my son at ease before treatment. She talks to him directly and in an age appropriate way. My son looks forward to visiting her and the other staff. When I have questions about treatment she responds clearly and, during after hours, Dr. Gandhe responds very quickly. We feel well cared for."
Amy M.
"Dr. Gandhe gives us excellent personalized treatment for my son’s peanut and tree nut allergy. She has a heart for kids with allergies and I feel very safe under her care. My son has already made great progress with his tree nut allergy"
Nikko Y.
"Best Office Ever!"
Georgia B.
"One of the best doctors + staff I have ever met. The care and professionalism is out of this world! We feel comforted and safe at our visit "
"Dr. Jain is very kind and friendly as well as the staff "
Graciela R.
"Dr.Jain and Melissa Hutton PA-C are the best allergy providers I have ever had the pleasure of meeting. The entire staff is kind and helpful. My allergy care is comprehensive and I never feel rushed through an appointment-"
"Best decision we have made in my son’s life so far"
Merritt F.
"We are very confident with Dr. Jain’s treatment plans and recommendations. The staff at the Fremont office is amazing"
Cherylyn V.
"Amazing and awesome team for scary and life-threatening allergies"
Manalie J.
"Dr.Gandhe is very patient, explains everything in great detail and answered all of our questions. It helped to ease out our Anxiety about OIT"
Walter M.
"Dr. Gandhe is great, thoughtful, and a caring provider. All staff is fantastic as well!"
Sarah S.
"We are likely (5 stars) to recommend Dr. Jain to friends and family. Our experience here has been so positive and supportive. It is great clinic and has given us great hopes in treating our son"
Khushi P.
"Extremely great experience. Truly God sent figures. Dr. Jain and Melissa are such wonderful and humble doctors, I have ever met. Thank You. Dr Jain and the entire staff for being with us through the journey. I will recommend him to all the people that I know with allergies
Amrita M.
"Dr. Gandhe has been more than a blessing for us. We love her! She’s so great at talking explaining and planning everything. Her treatment has been spot on and I am so thankful we found you. We love all the nurses, they are so patient and loving"
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